With the opening of the 2015-2016 school year, Manila Science High School witnessed a changing of the guards with the return of Ms. Maria Eva S. Nacion taking on the role of the school's 9th principal. We say "the return" as Ms. Nacion was once a faculty of MaSci, teaching science subjects back in the mid-2000's.
Prior to returning to MaSci, Ms. Nacion was the principal of F.G. Calderon High School. There she instituted effective reforms that benefited her constituents. She replaced outgoing MSHS principal Mrs. Pura Talattad effective June 15, 2015.